I have created a new site. When I open the site using the URL the browser gives this.

HTTP/1.1 404
Connection: close
Date: Tue, 01 Feb 2011 15:44:05 GMT
Server: Microsoft-IIS/6.0
X-Powered-By: ASP.NET
MicrosoftSharePointTeamServices: 12.0.0.4518

Solution :

• The most probably reason is you haven’t create the Top-Level site collection.

• SPS will not create the Top-Level site collection for you by default. To create the Top-Level site collection, goto Central Administration > Application Management > Create Site Collection.